Endocrine Abstracts

Aim: Vitamin D insufficiency is associated with an increase in PTH, which might be critical for an increase in bone fragility. However, the role of endogenous PTH in vitamin D insufficiency-induced increase in fracture risk still remains unclear. The present study was performed to examine the relationships among vitamin D insufficiency, bone fragility, PTH and sclerostin, which is produced by osteocytes and inhibits bone formation by inhibiting the Wnt pathway.<p class="ab...